We present a practical guide and step-by-step flowchart for establishing uncertainty intervals for key model outcomes in a simulation model in the face of uncertain parameters.The process starts with Powell optimization to find a set of uncertain parameters (the optimum parameter set or OPS) that minimizes the model fitness error relative to histor
Inborn defects here of the tricarboxylic acid (TCA) cycle enzymes have been known for more than twenty years.Until recently, only recessive mutations were described which, although resulted in severe multisystem syndromes, did not predispose to cancer onset.In the last ten years, a causal role in carcinogenesis has been documented for inherited and
Vertebrate tracks are subject to a wide distribution of morphological types.A single trackmaker may be associated with a range of tracks reflecting individual pedal anatomy and behavioural kinematics merlin wizard costume mediated through substrate properties which may vary both in space and time.Accordingly, the same trackmaker can leave substanti
In this paper we discuss several consequences of the freight transnational rail liner service on the rail corridor capacity.The Northern part of the IVth TEN-T corridor on Romanian territory has specific feature related to the passenger flows connecting important Romanian demographic and economic clusters, on one side, and on the other side, to its